A Computational Fluid Dynamics Study on Venous Valve Function within Aneurysmal Venous Geometries

Articles in Press

Document Type : Original Research Paper

Authors

1 University of Bonab

2 School of Mechanical Engineering, University of Tabriz, Tabriz, Iran

10.22111/cnmst.2026.55105.1295

Abstract

This numerical study investigates venous valve function and altered hemodynamics within aneurysmal veins, where vein wall dilation compromises valve effectiveness. Using Computational Fluid Dynamics (CFD) in COMSOL Multiphysics, we simulated blood flow in a two-dimensional model of an aneurysmal vein segment with valves, under pulsatile sinusoidal inlet conditions. The analysis focused on velocity profiles, pressure distributions, and Von Mises stress evolution over six seconds. Results indicate significant deviations from healthy flow patterns within the aneurysm. Pronounced flow separation and recirculation zones were observed downstream of the valves, correlating with elevated Von Mises stress concentrations on the vein wall, particularly at curvatures and impingement areas. The dynamic analysis highlights compromised valvular function and increased mechanical load on the dilated venous wall. Validation against experimental ultrasound data showed good agreement, with flow parameter errors between 2.2% and 3.6%. These findings underscore the critical role of hemodynamics in venous aneurysm progression and demonstrate the utility of numerical simulations for detailed insights into valve performance and wall mechanics. This research enhances understanding of aneurysmal vein pathophysiology and may inform diagnostic and therapeutic strategies for venous valve dysfunction.

Keywords

Challenges in Nano and Micro Scale Science and Technology

Articles in Press, Accepted Manuscript
Available Online from 06 September 2026

Files

Share

How to cite

Statistics